1. Combined Mycobacterium tuberculosis nucleic acid amplification test and rifampicin and isoniazid resistance detection
    Combined Mycobacterium tuberculosis nucleic acid amplification test and rifampicin and isoniazid resistance detection
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Moderate-complexity automated NAAT
  2. Combined Mycobacterium tuberculosis nucleic acid amplification test and rifampicin resistance detection
    Combined Mycobacterium tuberculosis nucleic acid amplification test and rifampicin resistance detection
    HIV infection, Meningitis, Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Low-complexity automated NAAT
  3. Culture-based drug susceptibility testing of antituberculosis drugs
    Solid medium (Löwenstein–Jensen medium, Middlebrook 7H10 or 7H11 agar media)
    Culture-based drug susceptibility testing (DST) of antituberculosis drugs
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Manual techniques
  4. Culture-based drug susceptibility testing of antituberculosis drugs
    Liquid medium
    Culture-based drug susceptibility testing (DST) of antituberculosis drugs
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Automated systems
  5. Interferon-gamma release assay
    Interferon-gamma release assay (IGRA)
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    ELISPOT assay
    Immunoassay
  6. Lipoarabinomannan antigen
    Lipoarabinomannan (LAM) antigen
    HIV infection, Tuberculosis (TB)
    Setting
    Non-laboratory
    Assay format
    Lateral flow RDT
  7. Mycobacterial culture
    Solid medium (Löwenstein–Jensen medium, Middlebrook 7H10 or 7H11 agar media). WHO recommended in 2025 WRDs (molecular techniques)
    Mycobacterial culture
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Manual techniques
  8. Mycobacterial culture
    Liquid medium
    Mycobacterial culture
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Automated systems
  9. Mycobacterium tuberculosis nucleic acid amplification test
    Mycobacterium tuberculosis nucleic acid amplification test
    HIV infection, Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Low-complexity manual NAAT
    Low-complexity automated NAAT
    Setting
    Laboratory
    Assay format
    Moderate-complexity automated NAAT
  10. Nucleic acid amplification test for detection of TB drugs resistance
    Nucleic acid amplification test for detection of TB drug resistance
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Low-complexity automated NAAT
  11. Nucleic acid amplification test for detection of TB drugs resistance
    First-line drug LPAs and second-line drug LPAs
    Nucleic acid amplification test for detection of TB drug resistance
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Line probe assays (LPAs)
  12. Nucleic acid amplification test for pyrazinamide resistance detection
    Nucleic acid amplification test for pyrazinamide resistance detection
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    High-complexity reverse hybridization NAAT
  13. Nucleic acid amplification test for rifampicin and isoniazid resistance detection
    Nucleic acid amplification test for rifampicin and isoniazid resistance detection
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Moderate-complexity automated NAAT
  14. Nucleic acid amplification test for rifampicin resistance detection
    Nucleic acid amplification test for rifampicin resistance detection
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Low-complexity automated NAAT
  15. Targeted next-generation sequencing for detection of TB drug resistance
    Targeted NGS end-to-end solutions recommended for the detection of resistance to specific anti-TB agents can be found in the targeted NGS section within the 2025 WHO operational handbook on tuberculosis. Module 3: diagnosis available at https://iris.who.int/handle/10665/382121
    Targeted next-generation sequencing for detection of TB drug resistance
    Tuberculosis (TB)
    Setting
    Laboratory
    Assay format
    Next-generation sequencing (NGS)
  16. Tuberculin skin test
    This is not an IVD test
    Tuberculin skin test (TST)
    Tuberculosis (TB)
    Setting
    Non-laboratory
    Assay format
    Mantoux test