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Indication - Tuberculosis (TB)
Lipoarabino-mannan (LAM) antigen
Facility level:
Assay formats
RDT
Status history
First added in 2018
Changed in 2020
Purpose type
Aid to diagnosis
Purpose
To aid in the diagnosis of TB in seriously ill HIV-positive in-patients and in HIV-positive adult out-patients with signs and symptoms of TB
Specimen types
Urine
WHO prequalified or recommended products
The use of lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis and screening of active tuberculosis in people living with HIV: policy update (2015) http://apps.who.int/iris/handle/10665/193633
WHO supporting documents
Lateral flow urine lipoarabinomannan assay (‎LF-LAM)‎ for the diagnosis of active tuberculosis in people living with HIV: policy update 2019 https://apps.who.int/iris/handle/10665/329479 https://www.who.int/health-topics/tuberculosis#tab=tab_1
Codes
ICD11 code: 1B1Z

Summary of SAGE IVD recommendation

The selection of the disease specific diagnostics tests for the EDL took into account the relevant priority diseases for the WHO such as HIV infection, tuberculosis, malaria, viral hepatitis B and C, syphilis and HPV infection. For these diseases there are WHO guidelines and technical reports, including recommendations for the appropriate IVDs. These documents are the result of significant evidence review and formed the basis for the inclusion of these IVDs in the EDL.

Details of submission from 2020

The inclusion of this entry was based on WHO guidelines and technical reports that include recommendations for the appropriate IVDs.