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Discipline -
Haematology
Direct antiglobulin test (DAT), also known as direct Coombs test
Assay formats
Haemagglutination
Status history
First added in 2019
Changed in 2020
Purpose type
Aid to diagnosis, Diagnosis
Purpose
To aid in the diagnosis of the cause of immune haemolytic anaemias;
To investigate a blood transfusion reaction;
To diagnose haemolytic disease of the newborn (HDNB)
Specimen types
Venous whole blood
Summary of SAGE IVD recommendation
General In vitro diagnostics tests are the general core and routine laboratory tests for clinical chemistry, haematology, blood transfusion, microbiology (virology, bacteriology, parasitology and mycology) and histopathology. These tests were selected on the basis of the scientific validity of an analyte, i.e. the association between an analyte and a clinical condition or physiological state; and clinical utility. Many of these tests are required for effective management of patients and have already been described in WHO publications.